参考文献
[1] http：//www.nhc.gov.cn/ylyjs/pqt/202304/464593bc8ce5489dbac1b2e0881a3f96.shtml
[2]Vedeld HM，et al.Early and accurate detection of cholangiocarcinoma in patients with primary sclerosing cholangitis by methylation markers in bile[J].Hepatology， 2022； 75：59–73.
[3] Sartore-Bianchi A,et al.European Journal of Cancer.2016,71:43-50
[4] Barault L，et al.Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer［J］．Ann Oncol，2015，26 (9)：1994-1999．
[5] Faaborg L , Andersen R F , Waldstrm M , et al. Prognostic Impact of Circulating Methylated Homeobox A9 DNA in Patients Undergoing Treatment for Recurrent Ovarian Cancer[J]. Cancers, 2022, 14(7):1766.
[6] Mary Alikian,et al.Molecular techniques for the personalised management of patients with chronic myeloid leukaemia[J].Biomolecular Detection and Quantification,2017,11(C):4-20.
[7] Goh Hyun-Gyung，et al.Sensitive quantitation of minimal residual disease in chronic myeloid leukemia using nanofluidic digital polymerase chain reaction assay.[J].Leukemia & lymphoma，2011，52(5)：896-904.